Cortisol Defense

Cortisol Defense® helps your body resist and recover from the effects of everyday stress. Components of this multifunctional formula have been shown to support healthy cortisol levels, help alleviate occasional fatigue, promote mental clarity, and support relaxation and restful sleep.*

Why does Dr. Jockers use Cortisol Defense?

Cortisol Defense is a multifunctional herbal supplement that has far-reaching and complementary benefits for individuals seeking help in dealing with everyday stress. It features a unique combination of clinically tested and patented ingredients, including Relora®, Sensoril®, and Suntheanine®, along with banaba leaf and maral extracts.

Together, these herbs help the overstressed body and mind work toward their normal state of balance and resolve many of the biochemical changes that occur as a result of repeated, frequent exposure to stressors and cortisol.*

What are the key ingredients?

Lemon Balm  (Magnolia Officinalis):

Relora® is a patented and proprietary blend of Magnolia officinalis and Phellodendron amurense bark extracts standardized to honokiol and berberine, respectively. These herbs have a history of traditional use in treating stress and occasional feelings of anxiousness.

In modern times, they and their actives (honokiol and berberine) are used to support relaxation and reduce the perception of stress and stress-related eating. Rodent stress studies demonstrate a reduction in induced feelings of anxiousness.[1,2]

Human studies demonstrate positive changes in DHEA (dehydroepiandrosterone) and cortisol levels, less weight gain (compared to controls), and reductions in perceived stress and transitory feelings of anxiousness in subjects taking Relora (500 mg to 750 mg for four to six weeks).[2-5]

Ashwagandha (Withania somnifera):

Sensoril® is an optimized ashwagandha (Withania somnifera) root and leaf extract that represents a major advancement in ashwagandha preparations. Sensoril’s proprietary and patented extraction process produces very high, powerful levels of stress-fighting, cognition-enhancing ashwagandha bioactive constituents.

In fact, Sensoril is standardized to a minimum of 10% glycowithanolides. Sensoril’s excellent safety record is one of the most comprehensive of any ashwagandha ingredient sold.*

Ashwagandha has been revered as an adaptogen for thousands of years. It is used to balance, energize, and revitalize the body and for its value as a cognition enhancer. Sensoril possesses multiple health benefits, and its superior efficacy has been demonstrated in randomized, double-blind, placebo-controlled human clinical trials. [6-10]

The results of these trials revealed that Sensoril, taken in doses of 500 to 1000 mg/d, supported healthy cortisol and DHEA levels; enhanced working memory, reaction time, and cognitive capacity; improved auditory-verbal working memory; ameliorated negative changes in cardiovascular parameters associated with mental stress; and improved endothelial function and glucose and lipid metabolism.*

L-Theanine:

Suntheanine® is a pure form of L-theanine that is produced via a patented fermentation process, resulting in a 100% pure L-isomertheanine. Clinical research suggests that 50 to 200 mg/d of Suntheanine naturally stimulates activity in the brain known as alpha waves, which are associated with a relaxed but alert mental state. [11]

L-theanine had significant anti-stress effects on experimental animals under psychosocial stress.[12] In humans, similar results were observed wherein L-theanine helped the body resist biochemical changes associated with stress.[13,14]

In a randomized, double-blind, placebocontrolled trial, a high dose of Suntheanine (400 mg/d) given to boys, aged 8-12 years, improved aspects of sleep quality, including significantly higher sleep percentage and sleep efficiency scores as well as a non-significant trend for less activity during sleep.*[15]

Banaba Leaf (Corosolic Acid):

Banaba Leaf (1% Corosolic Acid) and Maral Extracts Banaba leaf (Lagerstroemia speciosa) has a long history of use in folk medicine, particularly in Southeast Asia, as a glucose modulator. More recently, animal and human research on banaba leaf and its actives, including corosolic acid, suggest multiple mechanisms that influence glucose and lipid metabolism.[16,17]

Furthermore, corosolic acid inhibits the enzyme that facilitates the conversion of cortisone to cortisol.[18]

• Support healthy cortisol levels
• Support blood sugar
• Support mood issues

Maral Extract (Rhaponticum carthamoides):

This has been widely used in traditional Siberian medicine, mainly to treat overstrain and common weakness resulting from illness. It has also been used historically as a stimulant and a remedy to support male sexual function.*[19]

When does Dr. Jockers use this product clinically? 

I use this product with individuals who have high cortisol and stress hormone production.  The dosages that I use this product in are the following:

What is the recommended dosage? 

Normal Dosage:  1 capsule – 2x daily (in the morning and before bed or when cortisol rhythm is most disturbed)

Advanced Dosage:  2 capsules – 2x daily (in the morning and before bed or when cortisol rhythm is most disturbed)

*Always begin with the normal dosage and do not exceed these dosages unless told to by a trained healthcare practitioner who is managing your case closely.*

Contraindications: 

This product is contraindicated for pregnant and nursing individuals and those with very low blood pressure. 

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† These statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure or prevent any disease.