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    ImmunoCharge

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      Why Choose ImmunoCharge?

      Your immune system is a complex system that protects you from viruses, bacteria, parasites, and other pathogens. It is a complex system that’s essential for your health and survival. 

      Optimal immune support is important for your health at all times. As we face more stressful experiences it is even more important to strengthen your body with good immune support nutrients. 

      Your body was created to overcome the challenges from the environment.  However, you must be an active participant and work to make your body stronger and more resilient to stress.  Our 10:1 ImmunoCharge formula is designed to help you do that!


      Quercetin:

      Quercetin is a plant flavanol from the flavonoid group of polyphenols that adds color to plants and is mostly found in the skin and leaves of various plants.  Some of the best food sources include elderberry, red onions, cranberries, capers, kale, blueberries and apples.

      Quercetin helps to improve the functional properties of immune cells while downregulating the production of inflammatory cytokines and histamines that over stimulate the body’s inflammatory response (1, 2).

      Quercetin also works as a zinc ionophore and helps facilitate the movement of zinc into the cell and increase intracellular zinc levels.  This process helps reduce viral replication and improves the inflammatory process (3, 4).  


       

      Zinc:  

      Zinc is critical for balancing the immune system and keeping the Th-1 and Th-2 systems in check.  Zinc potentiates the action of the human cytokine interferon alpha, a protein that inhibits viral replication.  This reduces immunological stress and improves the immune coordination (5, 6).

      Zinc is also a very specific component of specific enzymes in the body including superoxide dismutatse enzymes (SODs).  SOD is a powerful intracellular antioxidant that protects the cellular genomics and prevents against viral infection and toxic debris accumulation within the cellular matrix.

      Zinc helps improve the bodies natural immunological response while keeping inflammatory activity from spiraling out of control (7).  


       

      Vitamin D:  

      Vitamin D plays an important role in both innate and adaptive immune responses. The active form of Vitamin D plays a key role in maintaining immune homeostasis (8, 9).  

      D3 is an immunomodulator targeting various immune cells, including monocytes, macrophages, dendritic cells, as well as T-lymphocytes and B-lymphocytes. Numerous large epidemiological studies and meta-analysis have linked inadequate vitamin D levels to a higher susceptibility of immune-mediated disorders including chronic infections and autoimmune diseases (10, 11)  


       

      N-Acetyl Cysteine:

      N-Acetyl Cysteine (NAC) is a source of essential amino acid L-cysteine, a precursor to the super antioxidant glutathione. Together, NAC and glutathione support the body’s antioxidant and detoxification activity. Glutathione is our most important antioxidant and is often deficient as we age or when we are exposed to a variety of toxins and infections.

      NAC also helps to break down excess mucus and acts as a protective shield during cold and flu season (12, 13, 14).  NAC offers the following health benefits:


       

      Vitamin C:

      Vitamin C is an essential antioxidant that supports both the innate and adaptive immune response with decades of research supporting its therapeutic properties.  White blood cells are under enormous oxidative stress when they attack pathogens.  To handle this oxidative stress, they need 50 times more vitamin C inside the cell than in the blood plasma.  

      Vitamin C acts to protect the endothelial lining of the blood vessels, lungs and other important tissues from pathogens and increased oxidative stress.  It also helps to tamper down inflammatory cytokines and improves immune coordination (15, 16).

      Vitamin C plays a critical role in the anti-viral response by activating the anti-viral interferon – α/β.  It also plays a role in decreasing the pro-inflammatory TNF-alpha and NF-Kb pathways that are associated with a higher rate of inflammatory activity in the body (17).  Vitamin C offers the following health benefits:

       

      Selenium:

      Selenium (Se) is an essential trace mineral that, through its incorporation into selenoproteins, plays a pivotal role in maintaining optimal health. Insufficient intake of Se enhances predisposition to diseases associated with oxidative stress to cells and tissues while supplementation above the recommended levels has been shown to confer health benefits such as enhanced immune competence and resistance to viral infections and in animal models and human studies (18).

      Selenium status is known to influence the functioning of all components of the immune system and its ability to respond to infections and cancers; Se is found in significant amounts in immune tissues such as spleen, lymph nodes and liver.  

      A selenium deficiency leads to reduced function of all immune cells and higher rates of viral infection and inflammation.  Adequate levels of Se are important for initiating immunity, but they are also involved in regulating excessive immune responses and chronic inflammation (19).  Selenium offers the following health benefits:

       

       

      Resveratrol:

      Resveratrol is the most well-known polyphenolic stilbenoid, present in grapes, blueberries, mulberries, rhubarb, and in several other plants. Resveratrol can play a beneficial role in the prevention and in the progression of chronic diseases related to inflammation such as diabetes, obesity, cardiovascular diseases, neurodegeneration, and cancers among other conditions. 

      Moreover, resveratrol regulates immunity by interfering with immune cell regulation, proinflammatory cytokines’ synthesis, and gene expression.  The effects of this biologically active compound on the immune system are associated with widespread health benefits for different autoimmune and chronic inflammatory diseases (20).

      The antiviral efficacy of Resveratrol has been demonstrated for several important viruses, including coronavirus. Resveratrol was shown to mitigate the major pathways involved in the pathogenesis of SARS-CoV-2, including regulation of the renin-angiotensin system (RAS) and expression of angiotensin-converting enzyme 2 (ACE2), stimulation of immune system and downregulation of pro-inflammatory cytokines release. It was also reported to promote SIRT1 and p53 signaling pathways and increase cytotoxic T lymphocytes (CTLs) and natural killer (NK) immune cells. (21)

       

      Magnesium:  

      Magnesium is one of the most abundant minerals in the human body and is used in over 300 different physiological processes. Unfortunately, magnesium is also one of the most pervasive deficiencies in our society today. 

      Magnesium and vitamin A are critical for the activation of vitamin D and many people will supplement with vitamin D but not get the desired benefit due to deficiencies in magnesium and vitamin A.

      A magnesium deficiency is associated with higher levels of inflammation, susceptibility to infection, trouble sleeping, muscle cramping, pain and poor healing processes (22).  Magnesium offers the following health benefits

         


        Vitamin A:  

        Vitamin A is an essential micronutrient for immunity, cellular differentiation, growth, reproduction, maintenance of epithelial surfaces and vision.  Vitamin A plays a critical role in the proper development of the mucosal membranes and in the growth and activation of T and B-cells (23).

        The epithelium lines all outer surface and most inner surfaces of organisms, and it functions as the “front line” of defense against pathogen invasion.  Vitamin A is critical for the development and protection of these surfaces and the production of the mucosal membranes which house the antigen non-specific immune defense.

        Vitamin A also plays a critical role in the activation of vitamin D within the cell so it can carry out its desired effect.  A vitamin A deficiency leads to higher viral and bacterial infection rates and higher morbidity and mortality associated with infectious diseases (24).  

         


        Vitamin K2:  

        Vitamin K is a fat-soluble nutrient that plays a critical role in blood clotting and calcium metabolism.  It is found in 2 major forms

        Vitamin K1 (phylloquinone) found in leafy green vegetables

        Vitamin K2 (menaquinone) found in dairy, egg yolk, fermented foods and animal products.

        Although these metabolites are both labeled in the vitamin K category, they have different functions.  Vitamin K1 is critical for blood clotting while vitamin K2 works as a vacuum getting calcium out of the blood stream and into the bones. This helps improve arterial health, blood flow and oxygenation into deep tissues of the body (25).

        Vitamin K2 also plays an important role in immune health and synergizes with vitamin D to optimize cardiovascular, dental and bone health. Insufficient levels of vitamin K2 are thought to increase the risk of cardiovascular calcifications and bone loss (26).  

        Vitamin K2 has also been shown to be an immunomodulator which helps improve the inflammatory response which may also be a contributing factor in improving cardiovascular and bone health (27, 28).  Vitamin K2 offers the following health benefits

         


        Introducing ImmunoCharge:

        ImmunoCharge is specifically designed to provide you with optimal dosages of these key immune modulating nutrients and compounds.  The synergy of these key nutrients and compounds strengthens immune function and improves the process of inflammation.

        Each ImmunoCharge capsule contains the same amount of powerful immune modulating compounds.  These include quercetin, resveratrol, vitamin D, vitamin A, selenium, zinc, vitamin C, N-Acetyl Cysteine, vitamin K2 and magnesium.  

        These ingredients support the body's natural immune mechanism to help maintain good health.  Rather than taking multiple different supplements to get these key nutrients, you can get the clinical dosages within 4 capsules daily of ImmunoCharge. 

        Directions:  

        Normal Dosage:  Take 2 capsules, 2 times daily with meals for optimal absorption, or as directed by your healthcare practitioner.

         

        Advanced Dosage:  Take 3-4 capsules, 2 times daily with meals for optimal absorption, or as directed by your healthcare practitioner.

         

        Consult your healthcare practitioner prior to use.  Individuals taking medication should discuss potential interactions with their healthcare practitioner.  Do not use if tamper seal is damaged.


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        KetoBrain C8 MCT Oil

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          Why Choose KetoBrain?

          KetoBrain C8 MCT Oil is extracted from natural sources using a three-stage steam-based filtering process without the addition of any chemicals. The result is a pure and ketogenic C8 (caprylic acid triglyceride) formulation.

            How Are MCTs Metabolized?

            MCTs are easily digested and do not require the production and utilization of bile (1). Most fatty acids depend upon bile salt emulsification in order to be metabolized and absorbed. The production of bile is an energy dependent process that takes place in the liver.

            Individuals with sluggish livers and gallbladders struggle to produce adequate bile. Other individuals who struggle with malnutrition or malabsorption syndromes can easily absorb and utilize these MCTs.

            MCTs have a remarkable ability to stabilize high blood glucose and enhance ketone body production. This process makes MCT’s a powerful tool to reduce inflammation, improve metabolism and enhance cognitive function.

            Why Choose C8 MCTs?

            Unlike long chain fatty acids, medium chain triglycerides (MCTs) are quickly converted into ketones and are less likely to be reserved as body fat. The result is improved mental performance and energy!

            Although C12 (lauric acid) is considered a medium chain triglyceride, it behaves in the body like a long chain fatty acid. Some brands include up to 50% lauric acid in their MCT oil. Choosing a MCT oil with only caprylic acid will provide the greatest health benefits.

              What Are Ketones?

              MCTs provide immediate energy because they are able to cross the double mitochondrial membrane very rapidly and do not require the presence of carnitine (2).

              The body has two major energy sources, it burns glucose or ketone bodies.  The majority of people burn glucose primarily because they are constantly supplying a steady form of sugar, starches and proteins that can be turned into blood glucose.  When one either fasts or goes on a low-carb, moderate protein and high fat diet they switch their energy source to fat.

              In particular, the fatty acids are broken down into ketone bodies.  The three major forms of ketones produced in the body include Acetoacetate, Acetone and Beta-HydroxyButyric acid.  These are released into the blood from the liver when insulin levels are low and hepatic liver metabolism is increased (3).

              Ketones are unique energy producing molecules made from fatty acids. Our bodies can make them from stored fat or from MCTs. Ketones feed all the cells of the body, but in particular they are a preferred fuel for the brain.

              Ketones activate specialized regulatory proteins in the brain called brain derived neurotrophic growth factors (BDNF). BDNF works to repair, protect and enhance the function of the brain cells and the neurological networks (4).

              BDNF also stimulates the growth of new, healthy neurons that take the place of older, dying cells. The inability to regulate dead or dying brain cells is a risk factor for neurodegenerative problems(5).

              Looking for Ways to Include MCT Oil?

              MCT oil is very versatile and also heat stable up to 320 o F. Use it as a salad dressing or a thickening agent for coffee and teas. Add it to smoothies to help curb hunger and keep you satisfied longer.

              Try it in one of my favorite coffee and dessert recipes!

              References:

              1. D C Harvey CJ, Schofield GM, Williden M, McQuillan JA. The Effect of Medium Chain Triglycerides on Time to Nutritional Ketosis and Symptoms of Keto-Induction in Healthy Adults: A Randomised Controlled Clinical Trial. J Nutr Metab. 2018; 2018:2630565. PMCID: 5987302
              2. Studzinski CM, et al. Induction of ketosis may improve mitochondrial function and decrease steady-state amyloid-beta precursor protein (APP) leavels in the aged dog. Brain Res. 2008 Aug; 1226: 209-17. PMID:18582445
              3. Kanikarla-Marie P, Jain SK. Hyperketonemia and ketosis increase the risk of complications in type 1 diabetes. Free Radic Biol Med. 2016; 95: 268–277. PMID: 4867238
              4. Maalouf M, Rho JM, Mattson MP. The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies. Brain Res Rev. 2009; 59(2):293–315. PMCID: 2649682
              5. Howells DW, et al.Reduced BDNF mRNA expression in the Parkinson’s disease substantia nigra. Exp Neurol. 2000 Nov; 166(1): 127-35. PMID: 11031089


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            Nitric Oxide Power

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              Why Does Dr. Jockers Like This Product?

              Nitric Oxide Power is oxalate free and utilizes MTHF for those who genetically have trouble converting dietary nitrate.

              What Are The Benefits?

              Blood Pressure and Circulation

              Nitric oxide has been clinically proven to support healthy blood pressure levels. The inside of the blood vessel is made up of smooth muscle. This is exactly where nitric oxide is also present. It triggers a biochemical reaction which prevents the constriction of these muscles. This causes the blood vessels to expand or open up. As a result of vasodilation, your heart does not have to exert itself too much to pump the blood with greater force.

              Sexual Health

              Female Sexual Arousal Disorder affects up to 70% of women, while the prevalence of moderate erectile dysfunction in the United States appears to be about 30%–50% in men aged 40–70 years old. A com-mon thread between male and female sexual function is how much both are impacted by insufficient circulation. Along with circulation, for females, nitric oxide acts as a neurotransmitter in the brain affecting the release of oxytocin and luteinizing hormone-releasing hormones, which are central in the modulation of sexual behavior.

              Cognitive Function

              Diminished blood flow to the brain may contribute to cognitive impairment. Adequate blood flow provides fuel and nutrients that may decrease the risk of age-related cognitive decline. Maintaining adequate nitric oxide levels in the aging brain protects many brain functions, including learning and memory.

              Immunity

              Adequate blood flow throughout the body allows for increased resistance to infections and provides the capability to localize offending agents. With good circulation and blood flow to every tissue in the body, the immune system can mobilize a strong defense against pathogens. 

               

              Research in the area of nitric oxide won the Nobel Prize in Medicine in 1998, yet its importance is still under appreciated by most.

              Why Choose Nitric Oxide Power?

              Our formulation stimulates N-O production without the use of arginine, beet root or spinach. 

              It has long been known that the Arginine pathway is not efficient or effective for people over 40. It has also become well known that Beets and Spinach are high in oxalates. We chose the highest N-O containing food as well as the lowest oxalate contributor- arugula.

              This formulation also utilizes L-5-MTHF (methyltetrahydrofolate) for those who genetically have trouble converting dietary nitrate.

              What Is The Recommended Use?

              The most reliable way to know if your levels of Nitric Oxide are insufficient is to use the 10 second test strip. Then take 2 capsules of Nitric Oxide Power and re-test in 90 minutes. Hydrate before and after. You may notice increased thirst while taking the supplements. 

              Any test strips for N-O are recommended.

              Always consult your trusted health professional before use. Not intended for pregnant or nursing women. 

              Common Concerns

              I can't swallow capsules. Can I open up the capsules and sprinkle over food? Yes! This does not reduce efficacy of the product.

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            Elderberry Zn Lozenge 90 count

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              Elderberry Zn Lozenge is a combination of zinc and elderberry delivered in an easy-to-dissolve lozenge with a delicious mixed berry flavor to support overall immune function.

              Ingredients

              Each lozenge provides 25 mg zinc (as zinc gluconate combined with zinc citrate), 100 mg elderberry fruit (Sambucus nigra) and has 0 g sugar. The lozenge delivery system is ideal for targeted absorption and may help support throat and upper respiratory tract health.

                Vital Role of Zinc

                Zinc is involved in virtually every aspect of the immune response. Adequate levels are essential for the healthy functioning of every cell in the body. The beneficial effects of zinc are extensive because this mineral is the body’s most abundant intracellular (i.e., inside the cells) trace element and at least 200 zinc-dependent enzymes have been identified.

                Some individuals are poor absorbers of this mineral, but most cases of zinc deficiency are due to poor diet, chronic stress, vegetarianism or excessive alcohol intake. Some deficiencies result from exposure to toxic metals, such as cadmium from cigarettes or excess copper from copper-lined tap water pipes.

                Zinc supports the actions of specific white blood cells that work to support the body’s immune system response to various pathogens. It is required for producing thymulin (the major thymus hormone) and therefore for the proper function of the thymus, the primary lymphoid organ where immune cells mature. A reduction of thymulin may lead to impaired immune function.

                Elderberry Supports Immune Health

                Elderberry, commonly referred to as European elder, is grown in most parts of Europe, North Africa, West Asia, and now the U.S., and nearly every part of the plant is utilized medicinally, as dietary supplements or for culinary purposes. The flowers and berries of Sambucus nigra are most often used medicinally and contain a variety of flavonoids that support healthy immune system function.

                Of all fresh fruits or berries, elderberry measures as one of the highest in antioxidant capacity and is one of the most commonly used botanicals in the world due to its immunologic properties and effects on inflammatory processes within the body.

                Recommended Use

                Take 1 lozenge per day, let dissolve slowly in mouth, or as directed by your health care practitioner. 

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